Cannabis and Depression: What You Need to Know

How Cannabis Affects Depression

The endocannabinoid system (ECS) helps regulate mood, motivation, and stress response. Cannabis compounds like THC and CBD interact with ECS receptors, influencing neurotransmitters such as dopamine and serotonin.

THC & Depression: Mood-Boosting or Risky?

• Low doses of THC can promote euphoria, relaxation, and creativity.
• High doses of THC may increase anxiety, paranoia, and lethargy.
• Chronic heavy THC use can lead to cannabis use disorder, worsening depressive symptoms.

CBD & Depression: A Natural Antidepressant?

CBD is non-psychoactive but interacts with serotonin receptors in a way similar to SSRIs (antidepressants). Studies suggest CBD may:

• Reduce stress and negative thought cycles
• Improve motivation and emotional regulation
• Enhance sleep quality, which is crucial for mental health

Best Strains for Depression

Strain	Type	Best For
Sour Diesel	Sativa	Energy & motivation
Jack Herer	Sativa	Uplifting creativity
Harlequin	Hybrid (High CBD)	Anxiety & mood stability
Northern Lights	Indica	Relaxation & stress relief

Key Takeaways

• THC can boost mood in low doses but may worsen depression if overused.
• CBD may help with emotional balance and stress management.
• Sativa strains support energy and motivation, while indicas promote relaxation and sleep.
• Cannabis is not a replacement for therapy or medication but can be a supportive tool.

If you're struggling with depression, consult a mental health professional before using cannabis as treatment.